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Health Now
An Integrative Approach to Personal Health

v3.1 Linda B. White

1.1 Defining Health and Wellness

Learning Objectives

  1. Define health and wellness.

  2. Analyze the relative contributions of medical care, genetics, personal behaviors, and environmental factors in determining health and longevity.

  3. Describe the dimensions of wellness.

What do you mean when you say someone is healthy? That the person lacks the outward signs of disease? That he or she appears physically fit? That his or her skin glows and eyes shine? Health is not always an easy word to pin down. For many years, health referred to the absence of disease. Western physicians examined the body for signs of physical illness, with little acknowledgment of other components of well-being.

In the mid-1940s, the World Health Organization (WHO) defined as “a state of complete physical, mental, and social well-being and not merely the absence of disease.” This definition of health has not changed since 1948. Optimal health allows people to enjoy long, productive lives.

Optimal health has become synonymous with . The WHO defines wellness as “the optimal state of health.” The organization further explains the two focal points of wellness: (1) “the realization of the fullest potential of an individual physically, psychologically, socially, spiritually and economically,” and (2) “the fulfillment of one’s role expectations in the family, community, place of worship, workplace, and other settings.” Optimum wellness is also termed “high-level wellness.”

Health and wellness are neither static nor passive. You are a work in progress. Some agents beyond your control—genetics, environmental exposures, age—affect your health. However, your lifestyle choices hold great power to either promote or undermine health. Wellness is an active process, one in which individuals deliberately adopt lifestyle patterns that promote their health. Most of us desire high-level wellness. And having a disability or chronic illness doesn’t prevent people from obtaining that goal.

No one lives forever. The maximum human lifespan is about 122 years. In 1997, a French woman named Jeanne Calment died at the age of 122, the longest anyone has ever lived. Although people increasingly make it to age 100, precious few live much longer. The average life expectancy in the United States is 78.8 years. Before death, many people have developed chronic (long-term) illnesses. In any given population of people, the gap between the actual and optimal state of health is known as the .

Determinants of Health

What makes one person healthy and another ill? Why do some people sustain long, vigorous lives while others suffer persistent illness and premature death? Research yields some surprising answers. For instance, only 10 percent of untimely deaths are caused by shortfalls in medical care. Family history and genetics contribute to 30 percent of illness and death. On the other hand, personal behaviors and environmental and social factors carry far greater weight in determining health and longevity.

Figure 1.1 Drivers of Premature Death

Four domains drive premature death. As you can see, insufficient medical care is responsible for only 10 percent of these deaths. While genetics and family history more powerfully shape health, a person’s behaviors are the most important. Furthermore, these domains interact.

Four gears labelled for the four domains, sized based on results. Personal behaviors (40%), Family history and genetics (30%), Environmental and social factors (20%), and Medical care (10%)

Another way to view health is from an ecological perspective. Ecology is a branch of biology that studies the complex relationships of organisms to one another and to their physical environments. In 1988, scientists began applying this model to human health. The basic concept is that multiple levels of influence affect human health. Furthermore, these levels interact in complex ways.

Figure 1.2 Social-Ecological Model of Health

Health can be viewed in an ecological framework, starting with an individual’s genetics and behaviors and expanding outward to social relationships, community resources, and greater societal influences.

Four concentric circles beginning with Individual at the center, then Relationship, Community, and Societal to show health framewrok

Figure 1.2 illustrates four levels: individual, relationship, community, and societal factors. You have the most control over your own health-related behaviors and the least over societal factors.

Individual Influences

Some of these factors are outside of your control: genetics, family history, age, gender, race, and sexual orientation. You have the power to modify other factors: beliefs and values, resiliency, coping skills, financial resources, education, health literacy, and health-related behaviors (diet, physical activity, sleep, substance use, sexual behaviors).

Relationships

Relationships include formal and informal social networks: family members, friends, roommates, classmates, coworkers, clubs, and support groups. Social support benefits health, particularly when friends and peers model and encourage health-promoting behaviors. In contrast, discord and violence undermine health; so does associating closely with people who abuse substances, engage in risky sexual behaviors, have consistently unhealthy diets, and disdain physical exercise.

Community Factors

Resources include the quality of neighborhoods, schools, religious institutions, housing, clinics and hospitals, parks and recreation centers, workplaces, air and water, and transportation. The cohesiveness of community members also figures in. In a pivotal examination of the health determinants, J. Michael McGinnis and colleagues wrote, “Our genetic predispositions affect the health care we need, and our social circumstances affect the health care we receive.”

Greater Societal Influences

Society and culture establish norms and attitudes about health-related issues such as diet, physical activity levels, body weight, smoking, substance abuse, sexuality, and violence. Intolerance and inequality based on gender, age, race/ethnicity, and sexual preference socially and economically marginalize those groups. The country’s overall economic health influences employment rates as well as the funding of social services, education, and health care. Environmental conditions directly impact health. Public health policies (public smoking bans, gun-control laws, seatbelt laws, universal vaccination, health insurance mandates) affect whole populations.

Family History and Genetics

In the past, discussions pitted genetics against environmental factors: nature versus nurture, genetic endowment as opposed to everything else—social environment, diet, activity levels, and environmental influences. However, we know nature and nurture interact intricately, engaging in a lifelong dance.

We inherit our genes from our parents. From there, ecology acts on those genes to affect our biology. Genetic traits can also color our responses to that ecology. So do the behaviors we learn from our parents, other role models, and the media. Multiple influences shape our physical, emotional, psychological, social, and financial health.

Within each of your cells (the basic working units in your body) is a nucleus, which contains your genetic information. The is the complete set of . DNA contains building blocks called nucleotides, which are arranged sequentially along chromosomes like beads on a necklace. The four nucleotide bases act like letters of the alphabet to spell out a code.

are threadlike structures containing DNA and protein. Humans have 23 chromosomes. Most cells contain a pair of each chromosome for a total of 46. (Sperm and egg cells contain 23 chromosomes.)

Each chromosome contains many genes. A is the basic unit of heredity. Each gene is made of a specific sequence of nucleotide bases and codes for a particular protein. In 2003, the U.S. Human Genome Project identified and sequenced all 20,500 human genes. The genome forms a blueprint for the structure and function of the body. As of 2018, the US Human Genome Project has discovered 1800 disease genes, which has led to over 2000 genetic tests to determine genetic risk and diagnosis of these diseases.

Proteins perform your body’s essential functions. They form structural components in your body (bones, ligaments, tendons, teeth, hair) and enzymes, which catalyze chemical reactions. The collection of proteins expressed by the genome is called the .

Only about 2 percent of deaths in this country are purely genetic in nature. Some diseases have a strong genetic component. A few are caused by a single mutated gene. Examples include sickle cell anemia (a mutation that distorts red blood cells), Tay Sachs disease (an enzyme deficiency that results in accumulations of fatty material in the brain), and cystic fibrosis (a defect that makes mucus sticky and difficult to clear in organs such as the lungs). Through advances in genomic medicine, scientists are learning to control, and perhaps someday cure, diseases caused by a single mutation.

Figure 1.3 The Chromosome

Inside the nucleus are the chromosomes, each of which contains many genes.

Diagram showing a chromosome.

Long Description

Image that helps to illustrate where the DNA can be found in a cell. The first illustration shows the nucleus within the cell. The next is of a chromosome within the nucleus. The chromosome is labeled to show the telomere, centromere, and chromatids. It then shows an illustration of a telomere and breaks that down to show the nucleosomes that make up the telomere. The illustration of the nucleosomes is broken down even further to show the histones. The next illustration shows the double helix of DNA and finally we see the four nucleotide base pairs of the DNA.

However, the marked health disparities and major diseases burdening the United States are not caused by genetic variations. The common chronic diseases of modern life stem from a complex interaction of genes, lifestyle habits, and environmental exposures. These so-called include common chronic conditions such as cardiovascular disease, diabetes, cancer, obesity, and Alzheimer’s disease. While these diseases may have genetic risks, they manifest from genetic vulnerability plus life experiences. As George Bray, MD, a renowned obesity researcher, famously put it, “Genetics loads the gun; the environment pulls the trigger.”

Our experiences and exposures modify , the conversion of genetic information into a protein. Not all genes are “read” (transcribed into proteins). That’s because, within the chromosomes, DNA is coiled around special proteins. In the chromosomes, the DNA winds around histones (a particular type of protein). Genes that are tucked within this coil can’t be read. Substances can also bind to genes (and their associated proteins) to prevent or allow their expression. Some genes promote or suppress the expression of other genes.

is the study of the reactions that influence gene expression. Epi is Greek for “above.” Epigenetics literally means above the genome. It explains why, despite sharing the same genes, a muscle cell looks different from a nerve cell and why the health of identical twins differs. Epigenetic changes can be inherited, even though the genes are not changed. Inherited traits, therefore, can be genetic or epigenetic.

Video Clip 1.1

Identical twins, by definition, share the exact same genes. However, environmental factors can alter the way our genes are expressed. That’s why identical twins aren’t really identical. Epigenetic changes can be passed along to the next generation. This Nova Science Now (PBS) video explains epigenetics, including the genetics and epigenetics of identical twins.

Prenatal and Early Childhood Experiences

Our experiences begin in the womb. Certain prenatal (before birth) exposures—malnutrition, toxins, infections—negatively affect the fetus’s growth and development.

In the late 1980s, David Barker, MD, PhD, professor of clinical epidemiology at the University of Southampton, England, and his colleagues showed that babies small at birth were at risk for developing high blood pressure and heart disease later in life. Provided with plenty of calories, low-birth-weight babies display catch-up growth and face a greater likelihood of becoming obese and developing diabetes.

Barker’s work sparked the “fetal origins of adult disease” hypothesis, which marked a radical departure from the belief in the 1950s that the fetus was largely protected from the mother’s experiences with alcohol, cigarettes, drugs, and stress. Instead, Barker and others posited that early life events can predispose people to chronic conditions that may not appear until middle age. Rather than changing the genes, these early experiences—good or bad—modify gene expression. Furthermore, epigenetic alterations can be passed to the next generation.

In addition to prenatal influences, negative experiences in childhood shape brain development, potentially leading to learning impairments, anxiety, depression, increased reactivity to stress, and substance abuse. Adverse childhood experiences have social, cultural, economic, and environmental roots. They contribute to and perpetuate disparities in health and socioeconomic status. The fetal origins hypothesis suggests that the best way to safeguard the health of the next generation is to optimize the health of their parents.

Video Clip 1.2

This music video explains genetics and epigenetic influences such as the prenatal environment.

Environmental Determinants of Health

People exercising in Haikou People’s Park, Haikou City, Hainan Province, China.

Haikou People’s Park

Environmental determinants are those physical elements that affect health. The natural environment includes plants, animals, natural resources, weather, and climate change. Access to natural landscapes (“green spaces”) positively influences human health.

The manmade environment gives us buildings (housing, workplaces, recreation centers, cultural events centers, industrial operations) and transportation. Our activities can both create aesthetically pleasing works and give rise to damaging pollutants.

As discussed, environmental influences begin before birth. Exposures to various chemicals can affect the eggs and sperm that combine to form an individual. The mother’s nutritional status, stress level, and overall health determine the environment in which a fetus develops. Early childhood experiences—some infectious diseases, abuse, neglect, family discord, and malnutrition—can have profound influences on health in adult life.

Throughout life, toxic exposures can increase the risk of cancer and other chronic diseases. Contaminants such as toxic chemicals and microorganisms in food, water, air, and soil pose health risks. Geographic location can determine exposure to noxious substances. Around the world, the poor are more likely than the rich to live near industrial operations and disposal sites for toxic waste. In developing countries, people often lack the luxury of clean drinking water. They may heat their homes by burning coal, which releases respiratory irritants.

The built environment shapes health. Buildings for residences and workplaces need to be safe. Communities designed for motor vehicle transportation promote inactivity and obesity. On the other hand, communities that create safe pedestrian and bicycle routes improve health by reducing pollution and encouraging physical activity. People with ready access to recreation centers and safe green spaces have better physical and mental health. Chapter 17 “Environmental Health” will discuss environmental health in more detail.

Socioeconomic Determinants of Health

Socioeconomic factors include your social experiences and economic realities. Socioeconomic status (SES) refers to one’s position in society based on education, occupation, and income. SES factors encompass social support, access to educational and job opportunities, availability of healthy foods, exposure to actual and media violence, prevailing attitudes and norms that relate to tolerance and acceptance, economic disparities, and the safety of neighborhoods. Included in this discussion are race (which is biologically based) and gender (which is biologically and culturally based) because they influence SES and contribute to health disparities.

Family

You inherit your genes from your biological parents. Your family also powerfully shapes your attitudes, values, eating habits, physical activity patterns, methods of managing stress, and social skills. Healthy families support and love one another, share responsibilities, eat together, enjoy leisure activities together, and don’t abuse substances. Well-nurtured children have better health and survival rates than those who face adversity.

Education

Educational level predicts health and longevity. Surveys show that college graduates are twice as likely as those who hadn’t graduated from high school to be in excellent health. Among people aged 45 to 64, the death rate for those with the highest level of education is 2.5 times lower than for people with the lowest education.

Education helps to close the racial-disparity gap between whites and nonwhites. One study found that, compared with whites with less than 12 years of education, blacks and Hispanics with 16 years of education lived an additional 7.5 and 13.6 years, respectively. Persistent racial discrimination and a two-tiered education system probably explain why most educated white men outlived the least educated black men by 14.2 years. The gap was 10.3 years for highly educated white women versus less educated black women. Death rates for those with higher levels of education are decreasing, whereas death rates for those with lower levels of education have remained steady or have increased.

Nevertheless, education promotes health for multiple reasons. Higher educational attainment correlates with better jobs, higher income, higher social status, health insurance coverage, less smoking, more physical activity, and less obesity. Taking a class in personal health gives you many tools and increases your health literacy, your ability to locate and understand health information, to obtain health services and to make informed health care decisions. Greater health literacy is linked to a reduced risk of hospitalizations, emergency room visits, and deaths.

Financial Status

Poverty contributes to an estimated 6 percent of (death). Income inequality (the difference in income between the richest and the poorest citizens) has widened over recent decades. For every 1 percent increase in income inequality, mortality rates rise 0.4 for those at the bottom. Possibly more important than absolute income level is how poor you feel. Feeling poor is stressful, which is bad for your health. Relative to more affluent neighborhoods, poor neighborhoods tend to have higher crime, worse pollution, suboptimal schools, scarcer grocery stores, and fewer parks and other green spaces—all of which undermine health and well-being.

Race and Ethnicity

refers to categories of people based largely upon physical appearance: the color of skin, hair, and eyes and the shape of the nose, eyes, and jaw. Ancestry influences these appearances. Ancestry also shapes , as do culture, nationality, language, traditions, and beliefs. While race is inherited, ethnicity is acquired. Any given race contains a host of ethnic groups. People who look white may identify with entirely different ethnic groups: Scandinavian, Australian, New Englanders, and so on. People with brown skin might fit into the pigeonhole for Hispanic yet be Dominican, Puerto Rican, Cuban, Spanish, or Brazilian.

The racial divisions used by the U.S. Census Bureau are white, black (African American), American Indian or Alaskan Native (also called Native Americans), and Asian (also called Asian American), Native Hawaiian, or Other Pacific Islander. Multiracial refers to a blend of two or more races.

Ethnicity affects health by influencing dietary patterns and attitudes toward education, substance use, physical activity, and health care. Only a few diseases fall along racial lines. For example, sickle cell disease mainly affects people of African and Mediterranean descent; cystic fibrosis tends to affect people of Northern European ancestry. Note that race is largely based on superficial biological characteristics. Of the genetic variation among humans, there’s far more variation within a continental group (e.g., Africans, Asians, Europeans) than between one race and another.

Nevertheless race contributes significantly to health disparities. Life expectancy at birth is 86.5 years for Asian-Americans, 82.8 years for Hispanics, 78.9 years for whites, 76.9 years for Native Americans, and 74.6 years for blacks (African-Americans). To survive into ripe old age, you need to make it out of childhood. In 2011, the infant mortality rate was more than twice as high for blacks as for whites, primarily due to premature birth. 

Causes of death and disease prevalence vary by race. For instance, in 2015 the number one cause of death in whites, blacks, and American Indians was heart disease. For Hispanics and Asian/Pacific Islanders, cancer is the top killer. Hispanics are more vulnerable to diabetes, blacks to stroke, and whites to Alzheimer’s disease. Relatively more deaths from accidents, liver disease, and diabetes affect American Indians and Alaska Natives.

A number of factors contribute to race-related health disparities. At the top of the list is racism, a bias toward or against members of a particular race. The presumption is that one race is somehow better or worse than another. Ungrounded stereotypes take root. Discrimination based on race hinders upward mobility among social classes and undermines health. Marginalization is stressful. Language barriers can further hamper the success of immigrants.

Underprivileged racial minorities more often live in poor neighborhoods marred by substance use, violence, substandard housing, and suboptimal schools. Green spaces, parks, recreation centers, and grocery stores (stocked with fresh produce) are often in short supply. Access to health care may be limited. Some experts believe that social conditions are the main causes of racial health disparities and far outweigh biological risk factors and access to medical technology.

Gender

Sex is biologically based. The World Health Organization defines gender as “the socially constructed roles, behaviors, activities, and attributes that a given society considers appropriate for men and women.” American women outlive men by five years. Life expectancy for a girl born in 2015 was 81.2 years versus 76.3 years for a boy. A complex interplay of biological and cultural differences contributes to this difference. Hormonal differences affect vulnerabilities to certain illnesses. Women are more likely to suffer from depression and osteoporosis (brittle bones). Men are more likely to die from accidents and violence. Women more often consult with health professionals for preventive care and sick care. Chapter 6 “Social and Gender Health” will discuss theories about gender-based health disparities in more detail.

Medical Care

Conventional medical care has a limited effect on people’s health. Insufficient medical care accounts for an estimated 10 percent of deaths. Researchers and scientists predict that, as the population continues to age (and requires more medical care), that number will rise. Older people tend to have more diseases, many of which can be managed by medical treatment. No matter one’s age, medical treatment can be lifesaving, particularly in the face of overwhelming infection or traumatic injury. Vaccinations prevent many infections that once cut life short. Medical technology helps diagnose and promptly treat many diseases.

On the other hand, medical care sometimes causes harm. A landmark 1999 study from the Institute of Medicine reported that as many as 98,000 people die each year from medical errors—more than deaths from car crashes, AIDS, and breast cancer. A 2016 study revealed that the problem was perhaps even worse. One out of three hospital patients in the United States experienced a medical error. Examples include hospital-acquired infections, adverse drug reactions, surgical injuries, and surgeries on the wrong site.

Personal Behaviors

Modifiable lifestyle patterns contribute to an estimated 20-40 percent of deaths. Each day, you make important decisions about diet, physical activity, substance use, and sex. You decide how you’ll handle life’s curveballs, whether you stress out or view them as challenges to master. You budget how much time you make for sleep and socializing.

Four unhealthy behaviors—lack of physical activity, poor diet, tobacco use, and excessive alcohol consumption—cause most of the illness and death related to chronic diseases. A British study tracked the impact on longevity of those four health behaviors over a span of eleven years. People with the lowest scores (smoked, didn’t exercise, drank too much, and didn’t consume at least five servings of fruit and vegetables a day) had four times the risk of dying relative to their peers who made the healthiest choices.

The Dimensions of Wellness

In a move away from examining health on the physical plane alone, experts have defined wellness according to six to seven dimensions. While some sources omit environmental wellness, physical environments clearly influence people’s health and well-being.

In Chapter 2 “Conventional, Complementary, and Integrative Medicine” we’ll discuss the holistic model, which holds that these dimensions interact and that optimal wellness requires that people mobilize their strengths and shore up weaknesses in all areas. For now, here are the seven dimensions and their attributes. In Chapter 1, Section 3 “Take Charge of Your Health” you’ll have a chance to assess your health in each area.

  1. Physical wellness. This takes into account a number of biological factors: level of physical fitness, presence or absence of disease or injury, and a person’s ability to take care of himself or herself.

  2. Emotional wellness. This refers to the overall balance of a person’s emotional state (happy, sad, angry, tranquil, etc.), awareness of emotions, and ability to express emotions freely and appropriately. People with positive emotional health are capable of trust, intimacy, and love. They are generally happy, optimistic, and self-confident and feel they accomplish what they set out to do.

  3. Social wellness. This springs from emotional wellness. Socially healthy people enjoy satisfying interpersonal relationships.

  4. Intellectual wellness. This refers to the ability to organize and express ideas; to think critically, rationally, and analytically; to maintain a sense of curiosity; and to solve problems using brainpower. Skills learned in the classroom can be used in life experiences. Creativity and zest for learning keep people vital and engaged throughout life.

  5. Spiritual wellness. This provides a sense of meaning and purpose in life. Spiritual people possess a set of beliefs, principles, and values that guide their decisions. They rise above intolerance, petty grievances, and grudges toward compassion, forgiveness, and altruism (a selfless concern for the well-being of others). They may have a sense of being part of a grander scheme. For many people, participation in organized religions forms the anchor of their spiritual life. Others may express their spirituality through creative arts, nature, meditation, and acts of service.

  6. Occupational wellness.  This entails identifying passions and career goals, preparing to meet those goals (which is one purpose of college), and finding work that pays the bills and provides a sense of personal satisfaction. Work can be paid or unpaid, including volunteer activities and scholastic pursuits. Financial stability is important. Its opposite generates stress and reduces access to healthy food, safe living situations, and health care—all of which jeopardize health. It’s also important to find a healthy balance between work and play. As a college student, you’re working on achieving that balance now.

  7. Environmental wellness. This refers to the safety and cleanliness of your physical environment, as well as your attitude toward the environment and your commitment to improving it. Environmental toxins can make you sick. On the other hand, beauty in your environment enhances your well-being. Your contributions toward protecting the planet—recycling, conserving natural resources, reducing pollution, preserving wilderness areas—have an impact and provide a sense of personal engagement.

Each of us moves along a continuum of health and wellness. Some days we feel under the weather; other days we’re brimming with vitality. In Chapter 1, Section 3 “Take Charge of Your Health” we’ll discuss the dimensions of wellness and the keys to promoting your own health and wellness.

Key Takeaways

  1. Health and wellness are more than the absence of disease.

  2. The most important determinant of health and longevity is personal behaviors. Genetic and family history, social factors, and environmental factors also influence health. Medical care, while critical, is the least important factor.

  3. Optimal wellness encompasses health in all the domains of a person’s life. The dimensions of wellness include physical, emotional, social, intellectual, spiritual, occupational, and environmental.

Discussion Questions

  1. Medical care has a relatively small contribution toward preventing premature death. Does that surprise you? Why do you think personal behaviors have a greater impact? Provide an example from your own life to support or dispute that contention.

  2. Some medical services do prevent illness and promote longevity and quality of life. Provide two examples of services you’ve received from your health provider that kept you healthy.

  3. Discuss the meaning of spirituality in your life. Consider what gives you a sense of meaning and purpose—the things you do that make you feel connected to something grander than yourself and the rituals you follow that make you at peace.

  4. In early 2018, British Prime Minister Theresa May appointed a minister for loneliness to address the societal challenge of loneliness. Loneliness has been thought to be as unhealthy as smoking 15 cigarettes per day. It can increase risk for heart disease, Type 2 diabetes, dementia, arthritis and suicide by increasing inflammation and stress hormones. How do you think loneliness effects health? How can you help combat this issue in your community?