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Nutrition Basics
An Active Approach

v3.0 Maureen Zimmerman, Mary Elizabeth Snow, and Jennifer K. Frediani

1.2 What Are Nutrients?

Learning Objectives

  1. Define the word nutrient and identify the six classes of nutrients essential for health.

  2. List the three energy-yielding nutrients and how much energy they each provide.

What’s in Food?

The foods we eat contain . Nutrients are chemical compounds in food that are used by the body to perform its functions and maintain health. Nutrients must be obtained from diet, since the human body does not synthesize them. Nutrients are used to produce energy, detect and respond to environmental surroundings, move, excrete wastes, respire (breathe), grow, and reproduce. There are six classes of nutrients required for the body to function and maintain overall health: carbohydrates, lipids, proteins, water, vitamins, and minerals. Foods also contain nonnutrients that may be harmful (such as dyes and preservatives) or beneficial (such as phytochemicals). Nonnutrient substances in food will be further explored in Chapter 8 “Nutrients Important as Antioxidants”.

Macronutrients

Nutrients that are needed in large amounts are called . There are three classes of macronutrients the body can use for energy: carbohydrates, lipids, and proteins. These can be metabolically processed into cellular energy. The energy from macronutrients comes from their chemical bonds. This chemical energy is converted into cellular energy that is then used to perform work, allowing our bodies to conduct their basic functions. A unit of measurement of food energy is the calorie. On nutrition food labels the amount given for “Calories” is technically kilocalories. A kilocalorie is one thousand calories (denoted with a small “c”), which is synonymous with the “Calorie” (with a capital “C”) on nutrition food labels. Water is also a macronutrient in the sense that you require a large amount of it, but, unlike the other macronutrients, it does not yield calories.

Carbohydrates

 are organic molecules composed of carbon, hydrogen, and oxygen that are found in food and living tissues. They typically contain hydrogen and oxygen in a 2:1 ratio, the same as in water (which is why they are called carbohydrates). The major food sources of carbohydrates are grains, milk, fruits, and starchy vegetables like potatoes. Nonstarchy vegetables also contain carbohydrates, but in lesser quantities. Carbohydrates can be categorized as sugars, starches, and fiber.

Sugars consist of one or two basic units. Examples of simple sugars include sucrose, the type of sugar you would have in a bowl on the breakfast table, and glucose, the type of sugar that circulates in your blood.

Slow-releasing carbohydrates are long chains of simple sugars that can be branched or unbranched. During digestion, the body breaks down all slow-releasing carbohydrates to simple sugars, mostly glucose. Glucose is then transported to all our cells, where it is stored, used to make energy, or used to build macromolecules.

Fiber is also a carbohydrate, but it cannot be broken down in the human body and instead passes through the digestive tract undigested unless the bacteria that inhabit the gut break it down.

One gram of carbohydrates yields four kilocalories of energy for the cells in the body to perform work. In addition to providing energy and serving as building blocks for bigger macromolecules, carbohydrates are essential for proper functioning of the nervous system, heart, and kidneys. As mentioned, glucose can be stored in the body for future use.

Figure 1.3 The Macronutrients: Proteins, Carbohydrates, Lipids, and Water

Diagram of the macronutrients which show its generic structures along with examples of where it is found. 

Long Description

The macronutrients are separated into four columns and labeled as follows from left to right: Proteins, Carbohydrates, Lipids, and Water. Below proteins is an illustration of its complex molecular structure, along with an image of a wedge of cheese, an egg, and two pieces of steak. Below carbohydrates is an illustration of its molecular structure and a slice of whole grain bread. Below lipids is an illustration of its structure, which show longer chains, along with an image of a glass bottle filled with oil. Below water is an image of its simple molecular structure, along with a glass of water.

Lipids

 are also a family of molecules composed of carbon, hydrogen, and oxygen, but unlike carbohydrates, they are insoluble in water. Lipids are found predominately in butter, oils, meats, dairy products, nuts, and seeds, and in many processed foods. The three main types of lipids are triglycerides (also called triacylglycerols), phospholipids, and sterols. The main job of lipids is to store energy. Lipids provide more energy per gram than carbohydrates (nine kilocalories per gram of lipid versus four kilocalories per gram of carbohydrate). In addition to energy storage, lipids serve as an important component of cell membranes, surround and protect organs, aid in temperature regulation, and regulate many other functions in the body.

Proteins

 are macromolecules composed of chains of subunits called amino acids. Amino acids are simple subunits composed of carbon, oxygen, hydrogen, and nitrogen. Food sources of proteins include meats, eggs, dairy products, seafood, and a variety of different plant-based foods, most notably soy. The word protein comes from a Greek word meaning “of primary importance,” which is an apt description of these macronutrients; they are also known colloquially as the “workhorses” of life. Proteins provide four kilocalories of energy per gram; however, providing energy is not protein’s most important function. Proteins provide structure to bones, muscles, and skin, and play a role in conducting most of the chemical reactions that take place in the body. Scientists estimate that more than one-hundred thousand different proteins exist within the human body.

Water

There is one other nutrient that we must have in large quantities: water. Water does not contain carbon, but rather is composed of two hydrogens and one oxygen per molecule of water. Approximately 60 percent of your total body weight is water. Without it, nothing could be transported in or out of the body, chemical reactions would not occur, organs would not be cushioned, and body temperature would fluctuate widely. According to the “rule of threes,” a generalization supported by survival experts, a person can survive three minutes without oxygen, three days without water, and three weeks without food. Since water is so critical for life’s basic processes, the amount of one’s water input and output is extremely important, a topic we will explore in detail in Chapter 7 “Nutrients Important to Fluid and Electrolyte Balance”.

Micronutrients

are nutrients required by the body in lesser amounts, but that are still essential for carrying out bodily functions. Micronutrients include all the essential minerals and vitamins. There are fourteen essential vitamins and and sixteen essential minerals. (Refer to Table 1.1 and Table 1.2 for a complete list and their major functions.) In contrast to carbohydrates, lipids, and proteins, micronutrients are not directly used for making energy, but rather assist in the process as being part of enzymes (i.e., coenzymes). Enzymes are proteins that catalyze chemical reactions in the body and are involved in all aspects of body functions, from producing energy, to digesting nutrients, to building macromolecules. Micronutrients play many roles in the body.

Vitamins

Vitamins are organic compounds that are required in small amounts for the body’s functioning and that cannot be produced by the body. The thirteen vitamins are categorized as either water-soluble or fat-soluble. The water-soluble vitamins are vitamin C and all the B vitamins, which include thiamine, riboflavin, niacin, pantothenic acid, pyroxidine, biotin, folate, and cobalamin. The fat-soluble vitamins are A, D, E, and K. Vitamins are required to perform many functions in the body, such as making red blood cells, synthesizing bone tissue, and playing a role in normal vision, nervous system function, and immune system function.

Vitamin deficiencies can cause severe health problems. For example, a deficiency in niacin causes a disease called , which was common in the early twentieth century in some parts of America. The common signs and symptoms of pellagra are known as the 4D’s—diarrhea, dermatitis, dementia, and death. Until scientists found out that better diets relieved the signs and symptoms of pellagra, many people with the disease ended up in psychiatric asylums awaiting death (refer to “Pellagra”). Other vitamins were also found to prevent certain disorders and diseases, such as scurvy (vitamin C), night blindness (vitamin A), and rickets (vitamin D).

Pellagra

This video provides a brief history of Dr. Joseph Goldberger’s discovery that pellagra was a diet-related disease.

1.75 to 4.417(gentle music)
5.9 to 6.99- [Narrator] One of the most influential
6.99 to 9.963public health figures of the
period is Joseph Goldberger.
12.39 to 15.09In 1914, he's summoned
by the surgeon general
15.09 to 18to investigate an
especially baffling disease
18 to 19.713ravaging the American South.
21.99 to 23.193It's called pellagra.
25.62 to 27.6The victims develop reddish, rough skin
27.6 to 30.243that often appears as a
butterfly-shaped rash.
34.77 to 36.63As the disease progresses,
36.63 to 39.81patients become confused, hallucinate,
39.81 to 41.283and finally go insane.
43.98 to 45.99There have been tens
of thousands of deaths
45.99 to 47.34in the rural South
47.34 to 50.043by the time Joseph Goldberger
has assigned the case.
52.71 to 54.69- At the time, it was a mystery disease,
54.69 to 58.08and people had many theories
about what caused it.
58.08 to 60.9The most prominent theory
60.9 to 63.81was that it was caused by eating corn,
63.81 to 65.49and there were other people who thought
65.49 to 68.73that it must be carried by an insect.
68.73 to 72.33This was fairly early on in
the bacteriological revolution,
72.33 to 73.56and so some people thought
73.56 to 75.723that it was carried by a bacteria,
76.77 to 78.66but no one knew.
78.66 to 81.03- [Narrator] Goldberger
journeys through the South
81.03 to 82.26to observe firsthand
82.26 to 84.753the conditions where
pellagra is most severe.
87.51 to 90.423Everywhere he travels, the
picture is strikingly similar:
91.62 to 94.8desperately poor people
working in cotton fields
94.8 to 97.953and textile mills,
suffering from the disease.
102.48 to 104.61Goldberger visits insane asylums
104.61 to 106.35and other state institutions
106.35 to 109.62where alarming numbers of
new cases are being reported.
109.62 to 112.38He knows the disease causes insanity,
112.38 to 115.2which might account for
the victims in asylums,
115.2 to 119.13but why is it so prevalent
in orphanages and prisons,
119.13 to 121.14and if it's an infectious disease,
121.14 to 123.363why isn't the staff getting sick as well?
124.59 to 127.23- One would think that if
this were a germ disease
127.23 to 131.433the germs certainly wouldn't
be aware of status boundaries.
132.33 to 135Why would only the inmates get pellagra,
135 to 138.12and why never a nurse, a
physician, or a teacher?
138.12 to 140.67- And he began to look at what people ate,
140.67 to 143.61and he was horrified at what he saw
143.61 to 146.13because the diet was so miserable,
146.13 to 149.13not like anything he had ever seen before.
149.13 to 152.76It was the diet of the southern frontier
152.76 to 155.553consisting primarily of cornbread,
157.14 to 160.503fatback or pork, and syrup.
161.34 to 162.69- [Narrator] Goldberger is well aware
162.69 to 165.51of the recent discoveries
of chemical elements in food
165.51 to 167.043called vitamins.
168.21 to 170.61He also knows that diseases like scurvy
170.61 to 174.39and beriberi have been linked
to vitamin deficiencies,
174.39 to 177.813and he suspects pellagra may
be the same kind of disease.
179.94 to 183.09Goldberger decides to test
his theory at two orphanages
183.09 to 185.883full pellagra victims
in Jackson, Mississippi.
188.85 to 192He starts by improving
the children's meager diet
192 to 194.76with fresh vegetables, meat, and milk.
194.76 to 197.82Foods rich in vitamins and proteins.
197.82 to 200.82- And lo and behold,
much to his own delight,
200.82 to 204.27the children who had pellagra got well
204.27 to 206.19when their diets were changed,
206.19 to 208.56and those who didn't have pellagra
208.56 to 212.88didn't contract pellagra after
their diets were changed.
212.88 to 214.59Well, that was all well and good
214.59 to 217.32but it certainly wasn't
scientific evidence,
217.32 to 220.14and Goldberger was very
much aware of that.
220.14 to 222.06- [Narrator] Goldberger
decides to show southerners
222.06 to 224.49that he can actually give people pellagra
224.49 to 226.173by simply changing their diet.
227.82 to 229.59He persuades the governor of Mississippi
229.59 to 232.05to pardon any convicts who volunteer
232.05 to 233.913for a controlled diet experiment.
236.43 to 238.71He chooses the Rankin Prison Farm
238.71 to 240.84because there are no cases of pellagra
240.84 to 243.843and plenty of room to isolate
the convicts from germs.
246.24 to 249.36- They were moved to a special building
249.36 to 251.52that had screens on the windows
251.52 to 254.04so that no insects could come in.
254.04 to 257.13It was scrubbed once
a week very carefully.
257.13 to 259.383They wore clean clothes every day.
260.28 to 263.01The only thing that was different
263.01 to 264.72about their lives, other than that,
264.72 to 266.193was the food that they ate.
268.5 to 269.79- [Narrator] Six months later,
269.79 to 272.377 of the 11 prisoners break out
272.37 to 274.803with the characteristic pellagra rash.
276.84 to 278.52Goldberger tells the pardoned men
278.52 to 281.76which foods they should
eat to cure their pellagra,
281.76 to 283.77and then waits for public acknowledgement
283.77 to 284.77of his breakthrough.
287.46 to 288.86But acceptance doesn't come.
290.46 to 293.26Some southerners even accuse
him of perpetrating a hoax.
294.45 to 295.98When he links pellagra to jobs
295.98 to 298.233that don't pay enough
for people to eat well,
299.07 to 301.62southerners hear only
his social criticism,
301.62 to 303.063not his medical reasoning.
305.55 to 308.22Goldberger, the scientist, is stunned
308.22 to 310.833by what he sees as total irrationality.
313.53 to 315.9Goldberger returns to the lab
315.9 to 317.4and dedicates the rest of his life
317.4 to 320.19to finding the specific cause of a disease
320.19 to 322.323he already knows how to prevent and cure.
324.06 to 326.43Eight years after Goldberger's death,
326.43 to 328.98scientists finally discovered that niacin,
328.98 to 331.983a B complex vitamin,
can prevent the disease.
332.85 to 334.863It's soon added to common foods.
338.49 to 340.05Today, there are no more cases
340.05 to 342.123of pellagra in the United States,
343.89 to 347.793and hardly anyone knows this
terrible disease ever existed.

Table 1.1 Vitamins and Their Major Functions

VitaminsMajor Functions
Water-soluble
B1 (thiamine)Coenzyme, energy metabolism assistance
B2 (riboflavin)Coenzyme, energy metabolism assistance
B3 (niacin)Coenzyme, energy metabolism assistance
B5 (pantothenic acid)Coenzyme, energy metabolism assistance
B6 (pyroxidine)Coenzyme, amino acid synthesis assistance
BiotinCoenzyme
FolateCoenzyme, essential for growth
B12 (cobalamin)Coenzyme, red blood cell synthesis
CCollagen synthesis, antioxidant
Fat-soluble
AVision, reproduction, immune system function
DBone and teeth health maintenance, immune system function
EAntioxidant, cell membrane protection
KBone and teeth health maintenance, blood clotting

Minerals

Minerals are solid inorganic substances that form crystals and are classified depending on how much of them we need. Trace minerals, such as molybdenum, selenium, zinc, iron, and iodine, are only required in a few milligrams or less, and macrominerals, such as calcium, magnesium, potassium, sodium, and phosphorus, are required in hundreds of milligrams. Many minerals are critical for enzyme function, while others are used to maintain fluid balance, build bone tissue, synthesize hormones, transmit nerve impulses, contract and relax muscles, and protect against harmful free radicals.

Table 1.2 Minerals and Their Major Functions

MineralsMajor Functions
Macro
SodiumFluid balance, nerve transmission, muscle contraction
ChlorideFluid balance, stomach acid production
PotassiumFluid balance, nerve transmission, muscle contraction
CalciumBone and teeth health maintenance, nerve transmission, muscle contraction, blood clotting
PhosphorusBone and teeth health maintenance, acid–base balance
MagnesiumProtein synthesis, nerve transmission, muscle contraction
SulfurProtein synthesis
Trace
IronCarries oxygen, assists in energy production
ZincProtein synthesis and DNA production, wound healing, growth, immune system function
IodineThyroid hormone production, growth, metabolism
SeleniumAntioxidant
CopperCoenzyme, iron absorption
ManganeseCoenzyme
FluorideBone and teeth health maintenance, tooth decay prevention
ChromiumAssists insulin in glucose metabolism
MolybdenumCoenzyme

Food Quality

One measurement of food quality is the amount of nutrients it contains relative to the amount of energy it provides. High-quality foods are nutrient dense, meaning they contain lots of the nutrients relative to the amount of calories they provide. Nutrient-dense foods are the opposite of “empty-calorie” foods such as carbonated sugary soft drinks, which provide many calories and very little, if any, other nutrients. Food quality is also associated with its taste, texture, appearance, microbial content, and how much consumers like it.

Key Takeaways

  1. Foods contain nutrients that are essential for our bodies to function.

  2. Four of the classes of nutrients required for bodily function are needed in large amounts. They are carbohydrates, lipids, proteins, and water, and are referred to as macronutrients.

  3. Two of the classes of nutrients are needed in lesser amounts, but are still essential for bodily function. They are vitamins and minerals.

  4. One measurement of food quality is the amount of essential nutrients a food contains relative to the amount of energy it has (nutrient density).

Discussion Starters

  1. Make a list of some of your favorite foods and visit the “What’s In the Foods You Eat?” search tool provided on the USDA’s website. What are some of the nutrients found in your favorite foods?

  2. Have a discussion in class on the “progression of science” and its significance for human health as depicted in the video on pellagra (refer to “Pellagra”).